Paul Lambrechts is born in 1955. He followed Latin-Greek studies at the ‘St. Jan Bergmanscollege’ of Diest. He graduated as a dentist (DDS) in 1978 at the Catholic University of Leuven (KULeuven), Belgium and obtained his PhD at the same university in 1983 based on a thesis investigating dental composites: "Basic properties of dental composites and their impact on clinical performance". He’s a specialist in microscopic endodontics, but also in aesthetic restorative dentistry. Today, he is Emeritus Professor at the Department of Conservative Dentistry (KULeuven). He teached cariology and endodontics. Together with his successor, Prof. Simon Pedano he still participates in the 3 year program of the Master after Master/Postgraduate in Endodontology.

He conducts research in endodontics, more specifically focusing on the development of a concept of minimal-invasive endodontic research, using 3D X-ray Micro-CT scanning, Nano-CT, Cone beam CT and Environmental SEM, towards new root-canal preparation and filling techniques. Advanced guided endodontics and navigation is actually under development. Revascularization and pulp regeneration is one of the new research challenges of his group, while the pathology of external cervical resorption is one of his favourite study topics. A randomized clinical trial on pulp revascularization is ongoing. Together with Prof. B. Van Meerbeek, he became in 2003 co-holder of the Toshio Nakao Chair for Adhesive Dentistry. He is (co-)promoter of several doctoral dissertations, and (co-) author of numerous publications (346) together with the Leuven BIOMAT Research Cluster. His h-index (Hirsch-index) is 75. He gives scientific and post-academic courses all over the world.